The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2008

Filed:

May. 18, 2006
Applicants:

Neal Jeffrey Green, Newton, MA (US);

Lori Krim Gavrin, Woburn, MA (US);

Neelu Kaila, Lexington, MA (US);

Yonghan HU, Acton, MA (US);

Kristin Marie Janz, Arlington, MA (US);

Jennifer R. Thomason, Revere, MA (US);

Ariamala Gopalsamy, Mahwah, NJ (US);

Steve Y. Tam, Wellesley, MA (US);

Lih-ling Lin, Concord, MA (US);

John William Cuozzo, Natick, MA (US);

Dennis William Powell, Cortlandt Manor, NY (US);

Inventors:

Neal Jeffrey Green, Newton, MA (US);

Lori Krim Gavrin, Woburn, MA (US);

Neelu Kaila, Lexington, MA (US);

Yonghan Hu, Acton, MA (US);

Kristin Marie Janz, Arlington, MA (US);

Jennifer R. Thomason, Revere, MA (US);

Ariamala Gopalsamy, Mahwah, NJ (US);

Steve Y. Tam, Wellesley, MA (US);

Lih-Ling Lin, Concord, MA (US);

John William Cuozzo, Natick, MA (US);

Dennis William Powell, Cortlandt Manor, NY (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/44 (2006.01); C07D 471/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R, R, R, R, Rr, m and n are defined as described herein. The invention also provides methods of making the compounds of formula (I), and methods of treating inflammatory diseases, such as rheumatoid arthritis, in a mammal comprising administering a therapeutically effective amount of a compound of formula (I) to the mammal.


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