The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2008

Filed:

Oct. 19, 2005
Applicants:

Marc Capet, Melesse, FR;

Denis Danvy, Yvetot, FR;

Nicolas Levoin, Mordelles, FR;

Marcel Morvan, Pace, FR;

Isabelle Berrebi-bertrand, Pace, FR;

Thierry Calmels, Melesse, FR;

Philippe Robert, Pace, FR;

Jean-charles Schwartz, Paris, FR;

Jeanne-marie Lecomte, Paris, FR;

Inventors:

Marc Capet, Melesse, FR;

Denis Danvy, Yvetot, FR;

Nicolas Levoin, Mordelles, FR;

Marcel Morvan, Pace, FR;

Isabelle Berrebi-Bertrand, Pace, FR;

Thierry Calmels, Melesse, FR;

Philippe Robert, Pace, FR;

Jean-Charles Schwartz, Paris, FR;

Jeanne-Marie Lecomte, Paris, FR;

Assignee:

Bioprojet, Paris, FR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 401/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds of the general formula (I): to the process for preparing them, and to the use thereof as a therapeutic agent having the property of being selective ligands for the dopamine D3 receptor. These selective D3 ligands are useful as medicines in neuropsychiatry, in particular in the treatment of psychotic or depressive states, or in the treatment of motor disorders, such as dyskinesia or essential tremor. They are furthermore useful in the treatment of dependency on nicotine, cocaine, alcohol, opioids and for facilitating withdrawal in drug-dependent individuals.


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