The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2008

Filed:

Feb. 18, 2002
Applicants:

Francis J. Carr, Balmedie, GB;

Graham Carter, By Newmachar, GB;

Tim Jones, Babraham, GB;

Stephen Williams, Insch, GB;

Anita Hamilton, Aberdeen, GB;

Inventors:

Francis J. Carr, Balmedie, GB;

Graham Carter, By Newmachar, GB;

Tim Jones, Babraham, GB;

Stephen Williams, Insch, GB;

Anita Hamilton, Aberdeen, GB;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 33/50 (2006.01); G06F 19/00 (2006.01); A61K 31/385 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to a novel approach for identification of T-cell epitopes, that give rise to an immune reaction in a living host. By means of this novel method biological compounds can be generated which have a no or at least a reduced immunogenicity when exposed to the immune system of a given species and compared with the relevant non-modified entity. Thus the invention relates also to novel biological molecules, especially proteins and antibodies, obtained by the method according to the invention.


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