The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2008

Filed:

Mar. 11, 2003
Applicants:

Marie-pierre T. M. M. G DE Bethune, Everberg, BE;

Sandra DE Meyer, Beerse, BE;

Kurt Hertogs, Antwerp, BE;

Rong Jian LU, Chapel Hill, NC (US);

Lieve Emma Jan Michiels, Mol, BE;

Abdellah Tahri, Anderlecht, BE;

Dong Xie, Germantown, MD (US);

Michael Eissenstat, Frederick, MD (US);

Inventors:

Marie-Pierre T. M. M. G De Bethune, Everberg, BE;

Sandra De Meyer, Beerse, BE;

Kurt Hertogs, Antwerp, BE;

Rong Jian Lu, Chapel Hill, NC (US);

Lieve Emma Jan Michiels, Mol, BE;

Abdellah Tahri, Anderlecht, BE;

Dong Xie, Germantown, MD (US);

Michael Eissenstat, Frederick, MD (US);

Assignee:

Tibotec Pharmaceuticals Ltd., County Cork, IE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 315/00 (2006.01); C07C 317/00 (2006.01); C07C 321/00 (2006.01); C07C 323/00 (2006.01); C07C 381/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns a compound having the formula (I) a N-oxide form, a stereochemical isomer, racemic mixture, salt, prodrug, ester or metabolite thereof. It further relates to processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors with anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS.


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