The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2008
Filed:
Feb. 12, 2003
Alexander William Oxford, Hertfordshire, GB;
Richard Anthony Borman, Cambridge, GB;
Robert Alexander Coleman, Hertfordshire, GB;
Kenneth Lyle Clark, Cambridge, GB;
George Hynd, Essex, GB;
Janet Ann Archer, Essex, GB;
Amanda Aley, Essex, GB;
Neil Victor Harris, Essex, GB;
Alexander William Oxford, Hertfordshire, GB;
Richard Anthony Borman, Cambridge, GB;
Robert Alexander Coleman, Hertfordshire, GB;
Kenneth Lyle Clark, Cambridge, GB;
George Hynd, Essex, GB;
Janet Ann Archer, Essex, GB;
Amanda Aley, Essex, GB;
Neil Victor Harris, Essex, GB;
Asterand UK Limited, Hertfordshire, GB;
Abstract
The present invention relates to compounds of formula I: wherein one of Rand Ris selected from the group consisting of H, and optionally substituted Calkyl, Ccycloalkyl, Ccycloalkyl-Calkyl, and phenyl-Calkyl; and the other of Rand Ris an optionally substituted Caryl group; Rand Rare either:(i) independently selected from H, R, R', SOR, C(═O)R, (CH)NRR, where n is from 1 to 4 and Rand Rare independently selected from H and R, where R is optionally substituted Calkyl, and R′ is optionally substituted phenyl-Calkyl, or(ii) together with the nitrogen atom to which they are attached, form an optionally substituted Cheterocyclic group; and their use as pharmaceuticals, in particular for treating conditions alleviated by the antagonism of a 5-HTreceptor.