The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2008
Filed:
Sep. 30, 2003
Sangita, Lucknow, IN;
Atul Kumar, Lucknow, IN;
Man Mohan Singh, Lucknow, IN;
Suprabhat Ray, Lucknow, IN;
Girish Kumar Jain, Lucknow, IN;
Sangita, Lucknow, IN;
Atul Kumar, Lucknow, IN;
Man Mohan Singh, Lucknow, IN;
Suprabhat Ray, Lucknow, IN;
Girish Kumar Jain, Lucknow, IN;
Counsel of Scientific and Industrial Research, New Delhi, IN;
Abstract
The present invention relates to compounds of the formula I in which substituents Rand Rare arranged in trans-configuration: wherein: wherein Y is chosen from NHR, NR, NHCOR, NHSOR, CONHR, CONR, CONR, COOH, COOR, SOR, SOR, SONHR, SONR, a C3-C7 heterocyclic ring, saturated or unsaturated, containing one or two heteroatoms independently selected from the group consisting of O, S and N, optionally being substituted with 1 to 3 substituents independently selected from the group comprising H, OH, halogen, nitro, cyano, SH, SR, trihalo-C1-C6-alkyl, C1-C6-alkyl and C1-C6-alkoxy, preferably NHR, NR, or a nitrogen heterocycle, wherein Ris as defined above, and the esters, ethers, and salts of the compounds of formula I, optionally along pharmaceutically acceptable excipients, a process for the preparation of the same, and a method of preventing and/or treating estrogen-related disease conditions in a subject using compounds of formula 1, or its salts, optionally along with pharmaceutically acceptable excipients.