The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2008
Filed:
Mar. 20, 2006
Raghavan Rajagopalan, Beechwood, OH (US);
Gary L. Cantrell, Troy, IL (US);
Samuel I. Achilefu, St. Louis, IL (US);
Joseph E. Bugaj, St. Charles, MO (US);
Richard B. Dorshow, St. Louis, MO (US);
Raghavan Rajagopalan, Beechwood, OH (US);
Gary L. Cantrell, Troy, IL (US);
Samuel I. Achilefu, St. Louis, IL (US);
Joseph E. Bugaj, St. Charles, MO (US);
Richard B. Dorshow, St. Louis, MO (US);
Mallinckrodt Inc., St. Louis, MO (US);
Abstract
The present invention discloses novel sulfenate derivatives and their bioconjugates for phototherapy of tumors and other lesions. The sulfenates of the present invention are designed to absorb low-energy ultraviolet, visible, or near-infrared (NIR) region of the electromagnetic spectrum. The phototherapeutic effect is caused by direct interaction of free radicals, the reactive intermediate produced upon photofragmentation of the sulfenate moiety, with the tissue of interest.