The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2008

Filed:

Sep. 10, 2002
Applicants:

Jerry Leroy Adams, King of Prussia, PA (US);

Deborah Lynne Bryan, King of Prussia, PA (US);

Yanhong Feng, Collegeville, PA (US);

Shinichiro Matsunaga, Tsukuba, JP;

Yutaka Maeda, Tsukuba, JP;

Yasushi Miyazaki, Tsukuba, JP;

Masato Nakano, Tsukuba, JP;

Jean-philippe Rocher, Vetraz-Mothoux, FR;

Hideyuki Sato, Tsukuba, JP;

Marcus Semones, Collegeville, PA (US);

Domingos J. Silva, Collegeville, PA (US);

Jun Tang, Tsukuba, JP;

Inventors:

Jerry Leroy Adams, King of Prussia, PA (US);

Deborah Lynne Bryan, King of Prussia, PA (US);

Yanhong Feng, Collegeville, PA (US);

Shinichiro Matsunaga, Tsukuba, JP;

Yutaka Maeda, Tsukuba, JP;

Yasushi Miyazaki, Tsukuba, JP;

Masato Nakano, Tsukuba, JP;

Jean-Philippe Rocher, Vetraz-Mothoux, FR;

Hideyuki Sato, Tsukuba, JP;

Marcus Semones, Collegeville, PA (US);

Domingos J. Silva, Collegeville, PA (US);

Jun Tang, Tsukuba, JP;

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 495/04 (2006.01); A61P 35/00 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Furo- and thienopyrimidine derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such furo- and thienopyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.


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