The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2008

Filed:

Aug. 01, 2003
Applicants:

Richard William Arthur Luke, Macclesfield, GB;

Clifford David Jones, Macclesfield, GB;

William Mccoull, Macclesfield, GB;

Barry Raymond Hayter, Macclesfield, GB;

Inventors:

Richard William Arthur Luke, Macclesfield, GB;

Clifford David Jones, Macclesfield, GB;

William McCoull, Macclesfield, GB;

Barry Raymond Hayter, Macclesfield, GB;

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/34 (2006.01); C07D 513/04 (2006.01); C07D 498/04 (2006.01); C07D 495/04 (2006.01); C07D 491/04 (2006.01); C07D 487/04 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound of the Formula (I), wherein A together with the carbon atoms to which it is attached forms a fused 5-membered heteroaryl ring, wherein said heteroaryl ring contains 1 or 2 heteroatoms selected from O, N and S, and wherein the 5-membered ring containing G is linked to the ring formed by A in the meta position to the bridgehead carbon marked # in Formula (I): G is selected from O, S and NR; Z is selected from N and CR; Qis selected from optionally substituted aryl and heteroaryl, and the substituents Rto Rare as defined in the text for use in the production of an anti-angiogenic effect in a warm blooded animal such as man.


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