The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2008
Filed:
Sep. 12, 2002
Douglas E. Brenneman, North Wales, PA (US);
Raquel Castellon, Norwalk, CA (US);
Catherine Y. Spong, Arlington, VA (US);
Janet M. Hauser, Bethesda, MD (US);
Illana Gozes, Ramat Hasharon, IL;
Douglas E. Brenneman, North Wales, PA (US);
Raquel Castellon, Norwalk, CA (US);
Catherine Y. Spong, Arlington, VA (US);
Janet M. Hauser, Bethesda, MD (US);
Illana Gozes, Ramat Hasharon, IL;
The United States of America as represented by the Secretary of the Department of Health and Human Services, Washington, DC (US);
Ramot at Tel-Aviv University, Ltd., Tel Aviv, IL;
Abstract
This invention relates to Activity Dependent Neurotrophic Factor I complex (ADNF I complex) and polypeptides of this complex, which produce their neurotrophic effects through multiple proteases intrinsic to the ADNF I complex. The invention also relates to pharmaceutical compositions comprising ADNF I complex polypeptides, as well as methods for reducing neuronal cell death in vitro and in vivo, methods for treating oxidative stress in a patient, methods for reducing a condition associated with fetal alcohol syndrome in a subject, and methods of enhancing learning and memory both pre- and post-natally, all of which methods use the ADNF I complex polypeptides of the invention.