The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2008

Filed:

Jun. 17, 2003
Applicants:

Steve A. Kay, San Diego, CA (US);

John B. Hogenesch, Encinitas, CA (US);

M. Fernanda Ceriani, Buenos Aires, AR;

Satchidananda Panda, San Diego, CA (US);

Inventors:

Steve A. Kay, San Diego, CA (US);

John B. Hogenesch, Encinitas, CA (US);

M. Fernanda Ceriani, Buenos Aires, AR;

Satchidananda Panda, San Diego, CA (US);

Assignees:

The Scripps Research Institute, La Jolla, CA (US);

IRM LLC, Hamilton, BM;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

Screening assays for identifying agents that modulate BK channel activity and further modulate the sleep/wake cycle in a subject, circadian regulated locomotor activity in a subject, or both are provided, as are agents identified using such screening assays. Also provided are methods of modulating the sleep/wake cycle in a subject and methods of modulating circadian regulated locomotor activity in a subject by administering an agent that modulates BK channel activity to the subject, for example, an agent identified by a screening assay as disclosed.


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