The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2008
Filed:
Jul. 23, 2003
David B. Agus, Beverly Hills, CA (US);
David B. Agus, Beverly Hills, CA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Abstract
Disclosed herein is a method for treating and preventing prostate cancer, and particularly androgen-independent prostate cancer, the method including administering to a mammal a benzothiopene having the formula or pharmaceutically acceptable salts or prodrugs thereof, wherein R and Rare each independently selected from the group consisting of hydrogen, —COR, —COR, and R; Ris selected from the group consisting of hydrogen, C1-C14 alkyl, C1-C3 chloroalkyl, C1-C3 fluoroalkyl, C5-C7 cycloalkyl, C1-C4 alkoxy, and phenyl; Ris phenyl with at least one substitution selected from the group consisting of C1-C4 alkyl, C1-C4 alkoxy, hydroxy, nitro, chloro, fluoro, trichloromethyl, and trifluoromethyl; Ris selected from the group consisting of C1-C4 alkyl, C5-C7 cycloalkyl, and benzyl; and Ris selected from the group consisting of oxygen and —C═O. The method may further include the administration of an estrogen lowering drug to enhance efficacy of the compound of the present invention.