The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2008
Filed:
Jun. 21, 2002
Yasunari Fujiwara, Tokyo-To, JP;
Terufumi Senga, Takasaki, JP;
Tsuyoshi Nishitoba, Tokyo-To, JP;
Tatsushi Osawa, Takasaki, JP;
Atsushi Miwa, Takasaki, JP;
Kazuhide Nakamura, Takasaki, JP;
Yasunari Fujiwara, Tokyo-To, JP;
Terufumi Senga, Takasaki, JP;
Tsuyoshi Nishitoba, Tokyo-To, JP;
Tatsushi Osawa, Takasaki, JP;
Atsushi Miwa, Takasaki, JP;
Kazuhide Nakamura, Takasaki, JP;
Kirin Beer Kabushiki Kaisha, Tokyo-To, JP;
Abstract
An objective of the present invention is to provide compounds having potent antitumor activity. The compounds of the present invention are represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof: wherein X=CH or N; Z=O or S; L=O or S; M=CRR, wherein Rand R=H, alkyl, or alkoxy, NRwherein R=H or alkyl; R, R, and R=H or optionally substituted alkoxy; R=H; R=H, halogen, alkoxy or the like; and R=alkyl optionally substituted by —R, -T-R, or —NRRwherein T=O, S, or NH; R=an optionally substituted carbocyclic or heterocyclic ring; and R=alkyl or an optionally substituted carbocyclic or heterocyclic ring, or —NRRwherein Rand R=H, optionally substituted alkyl, or an optionally substituted carbocylic or heterocyclic ring, or optionally substituted carbocyclic or heterocyclic ring.