The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2008
Filed:
Jul. 23, 2003
Futoshi Shiga, Shimotsuga-gun, JP;
Takahiro Kanda, Oyama, JP;
Tetsuya Kimura, Koga, JP;
Yasuo Takano, Kazo, JP;
Jyunichi Ishiyama, Saitama, JP;
Tomoyuki Kawai, Shimotsuga-gun, JP;
Tsuyoshi Anraku, Shimotsuga-gun, JP;
Kumi Ishikawa, Utsunomiya, JP;
Futoshi Shiga, Shimotsuga-gun, JP;
Takahiro Kanda, Oyama, JP;
Tetsuya Kimura, Koga, JP;
Yasuo Takano, Kazo, JP;
Jyunichi Ishiyama, Saitama, JP;
Tomoyuki Kawai, Shimotsuga-gun, JP;
Tsuyoshi Anraku, Shimotsuga-gun, JP;
Kumi Ishikawa, Utsunomiya, JP;
Kyorin Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
The invention provides 4-substituted aryl-5-hydroxyisoquinolinone derivatives and their pharmacologically acceptable addition salts with excellent inhibitory effect on poly (ADP-ribose) synthetase. 4-Substituted aryl-5-hydroxyisoquinolinone derivatives, represented by a general formula (1) and their pharmacologically acceptable addition salts.