The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2008

Filed:

Nov. 18, 2002
Applicants:

Roger Corder, Harrow, GB;

Adrian P. L. Smith, London, GB;

Timothy W. Higgenbottam, Sheffield, GB;

Martine Rothblatt, Silver Spring, MD (US);

John Vane, London, GB;

Delphine Dominique Marthe Lees, London, GB;

Inventors:

Roger Corder, Harrow, GB;

Adrian P. L. Smith, London, GB;

Timothy W. Higgenbottam, Sheffield, GB;

Martine Rothblatt, Silver Spring, MD (US);

John Vane, London, GB;

Delphine Dominique Marthe Lees, London, GB;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Sequences in human preproendothelin-1 mRNA are described against which antisense oligonucleotides can be used to inhibit the synthesis of endothelin-1. This inhibition of endothelin-1 synthesis may be used to treat diseases where excess production of endothelin-1 is an underlying cause of the symptoms.


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