The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2008
Filed:
Nov. 03, 2004
Gadi Gazit-bornstein, Mountain View, CA (US);
Giorgio Senaldi, Dublin, CA (US);
Xiao-dong Yang, Palo Alto, CA (US);
Bruce Keyt, Hillsborough, CA (US);
Gerardo Zapata, San Mateo, CA (US);
Gadi Gazit-Bornstein, Mountain View, CA (US);
Giorgio Senaldi, Dublin, CA (US);
Xiao-Dong Yang, Palo Alto, CA (US);
Bruce Keyt, Hillsborough, CA (US);
Gerardo Zapata, San Mateo, CA (US);
Amgen Fremont Inc., Fremont, CA (US);
Abstract
The present invention is related to antibodies directed to the antigen properdin and uses of such antibodies. In particular, in accordance with the present invention, there are provided fully human monoclonal antibodies directed to the antigen properdin. Nucleotide sequences encoding, and polypeptides comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.