The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2008

Filed:

Feb. 17, 2006
Applicants:

Johan Leban, Munich, DE;

Bernd Kramer, Aachen, DE;

Wael Saeb, Planegg-Martinsried, DE;

Gabriel Garcia, Munich, DE;

Inventors:

Johan Leban, Munich, DE;

Bernd Kramer, Aachen, DE;

Wael Saeb, Planegg-Martinsried, DE;

Gabriel Garcia, Munich, DE;

Assignee:

4SC AG, Martinsried, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/164 (2006.01); A61K 31/341 (2006.01); A61K 31/381 (2006.01); C07D 207/24 (2006.01); C07D 333/06 (2006.01); C07D 307/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a novel compounds that can be used as anti-inflammatory, immunomodulatory and antiproliferatory agents. In particular, the invention refers to new compounds which inhibit dihydroorotate dehydrogenase (DHODH), a process for their manufacture, pharmaceutical compositions containing them and to their use for the treatment and prevention of diseases, in particular their use in diseases where there is an advantage in inhibiting dihydroorotate dehyrogenase (DHODH).


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