The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2008

Filed:

Aug. 01, 2003
Applicants:

Marco Ciufolini, Lyons, FR;

Camille Wermuth, Strasbourg, FR;

Bruno Gielthen, Illkirch, FR;

Alain Moussy, Paris, FR;

Inventors:

Marco Ciufolini, Lyons, FR;

Camille Wermuth, Strasbourg, FR;

Bruno Gielthen, Illkirch, FR;

Alain Moussy, Paris, FR;

Assignee:

AB Science, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel compounds selected from 2-(3-aminoaryl)amino-4-aryl-thiazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.


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