The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2008

Filed:

Jun. 23, 2005
Applicants:

Pingda Ren, San Diego, CA (US);

Xia Wang, San Diego, CA (US);

Nathanael Schiander Gray, Boston, MA (US);

Yi Liu, San Diego, CA (US);

Taebo Sim, Chestnuthill, MA (US);

Inventors:

Pingda Ren, San Diego, CA (US);

Xia Wang, San Diego, CA (US);

Nathanael Schiander Gray, Boston, MA (US);

Yi Liu, San Diego, CA (US);

Taebo Sim, Chestnuthill, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5355 (2006.01); C07D 413/10 (2006.01); C07D 475/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders than involve abnormal activation of the Abl, Bcr-abl, Bmx, c-RAF, CSK, Fes, FGFR3, Flt3, GSK3β, IR, JNK1α 1, JNK2α 2, Lck, MKK4, MKK6, p70S6K, PDGFRα, Rsk1, SAPK2α, SAPK2β, Syk and Trkβ kinases.


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