The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Jul. 02, 2002
Reinhold Öhrlein, Rheinfelden-Herten, DE;
Gabriele Baisch, Binzen, DE;
Nicole End, Oberwil, CH;
Stephan Burkhardt, Gelterkinden, CH;
Martin Studer, Basel, CH;
Reinhold Öhrlein, Rheinfelden-Herten, DE;
Gabriele Baisch, Binzen, DE;
Nicole End, Oberwil, CH;
Stephan Burkhardt, Gelterkinden, CH;
Martin Studer, Basel, CH;
Ciba Specialty Chemicals Corp., Tarrytown, NY (US);
Abstract
The invention relates to synthesis methods for the preparation of statin derivatives, which methods proceed by way of a key intermediate of formula I wherein X is halogen, acyloxy, activated hydrocarbyloxy, activated hydrocarbylthio or N(CH)OCH, Ris a hydroxy-protecting group, and Ris a carboxy-protecting group, and, as well as to the compound of formula I, to further intermediates and methods for their preparation by Friedel-Crafts acylation.