The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Sep. 23, 2004
Kim Bojstrup Jensen, Kobenhavn O, DK;
Rikke Eva Humble, Kobenhaven NV, DK;
Ken Liljegren, Vaerlose, DK;
Troels Volsgaard Christensen, Holbaek, DK;
Kim Bojstrup Jensen, Kobenhavn O, DK;
Rikke Eva Humble, Kobenhaven NV, DK;
Ken Liljegren, Vaerlose, DK;
Troels Volsgaard Christensen, Holbaek, DK;
H. Lundbeck A/S, Copenhagen-Valby, DK;
Abstract
The present invention discloses crystalline particles of escitalopram oxalate which either have a broad particle size distribution or comprise at least 0.01% (w/w) of Z-4-(4-dimethylamino-1-(4-fluorophenyl)-but-1-enyl)-3-hydroxymethyl-benzonitrile, said particles being suitable for use in direct compression. Furthermore, the invention discloses a novel pharmaceutical unit dosage form containing such crystalline particles of escitalopram oxalate as well as methods for manufacture of such crystalline particles of escitalopram oxalate Finally, the invention provides a method for reduction of the amount of hydroxyl containing impurities in a solution of citalopram or escitalopram.