The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Oct. 11, 2005
Andrés Francesch, Madrid, ES;
Carolina Fernández, Madrid, ES;
José Luis Chicharro, Madrid, ES;
Pilar Gallego, Madrid, ES;
Maria Zarzuelo, Madrid, ES;
Ignacio Manzanares, Madrid, ES;
Marta Perez, Madrid, ES;
Carmen Cuevas, Madrid, ES;
María Jes{dot Over (U)}s Martin, Madrid, ES;
Simon Munt, Madrid, ES;
Andrés Francesch, Madrid, ES;
Carolina Fernández, Madrid, ES;
José Luis Chicharro, Madrid, ES;
Pilar Gallego, Madrid, ES;
Maria Zarzuelo, Madrid, ES;
Ignacio Manzanares, Madrid, ES;
Marta Perez, Madrid, ES;
Carmen Cuevas, Madrid, ES;
María Jes{dot over (u)}s Martin, Madrid, ES;
Simon Munt, Madrid, ES;
Pharma Mar, S.A., Madrid, ES;
Abstract
Processes are provided for preparing compounds with a fused ring structure of formula (XIV). Such products include ecteinascidins and have a spiroamine-1,4-bridge. The process involving forming a 1,4 bridge using a 1-labile, 10-hydroxy, 18-protected hydroxyl, di-6,8-en-5-one fused ring compound. After formation of the 1,4 brige, C-18 protection is removed before spiroamine introduction.