The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Dec. 19, 2003
Akira Tsuji, Kanazawa, JP;
Ikumi Tamai, Kanazawa, JP;
Yoshimichi Sai, Kanazawa, JP;
Noubuhiko Yui, Ishikawa, JP;
Toru Oya, Ishikawa, JP;
Ken-ichi Miyamoto, Tokushima, JP;
Akira Tsuji, Kanazawa, JP;
Ikumi Tamai, Kanazawa, JP;
Yoshimichi Sai, Kanazawa, JP;
Noubuhiko Yui, Ishikawa, JP;
Toru Oya, Ishikawa, JP;
Ken-ichi Miyamoto, Tokushima, JP;
Japan Science and Technology Agency, Saitama, JP;
Abstract
The present invention is to provide a tissue-specific transporter inhibitor which is not absorbed through the digestive tract and can prevent deterioration in the QOL of a patient caused by diet therapy, and a therapeutic drug for tissue dysfunction diseases and a therapeutic drug for suppressing the progress of chronic renal failure containing the inhibitor as an active ingredient. A tissue-specific transporter inhibitor which is not absorbed through the digestive tract is constructed by introducing a dipeptide which is a ligand of an oligopeptide transporter 1 into a supramolecular structure polyrotaxane wherein its structurally modified active residue is expected to be excellent in the interaction with a transmembrane transporter.