The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2008

Filed:

Jun. 09, 2003
Applicants:

Gian Luca Araldi, Plymouth, MA (US);

Adulla P. Reddy, Walpole, MA (US);

Zhong Zhao, Wayland, MA (US);

Sean D. Mckenna, Duxbury, MA (US);

Bagna Bao, Sharon, MA (US);

Inventors:

Gian Luca Araldi, Plymouth, MA (US);

Adulla P. Reddy, Walpole, MA (US);

Zhong Zhao, Wayland, MA (US);

Sean D. McKenna, Duxbury, MA (US);

Bagna Bao, Sharon, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4015 (2006.01); A61K 31/5377 (2006.01); C07D 207/27 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

1,2-substituted 5-pyrrolidinone compounds are provided, and methods of treatment and pharmaceutical composition that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing preterm labor, dysmenorrhea, asthma, hypertension, infertility or fertility disorder, undesired blood clotting, preeclampsia or eclampsia, an eosinophil disorder, sexual dysfunction, osteporosis and other destructive bone disease or disorder, renal dysfunction, an immune deficiency disorder, dry eye, ichthyosis, elevated intraocular pressure, sleep disorder, or gastric ulcer, inflammatory disorders and other diseases and disorders associated with the prostaglandin family of compounds.


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