The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Nov. 14, 2005
Applicants:
B. Narasimhulu Naidu, Durham, CT (US);
Timothy P. Connolly, Portland, CT (US);
Yasutsugu Ueda, Clinton, CT (US);
Inventors:
B. Narasimhulu Naidu, Durham, CT (US);
Timothy P. Connolly, Portland, CT (US);
Yasutsugu Ueda, Clinton, CT (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 9/40 (2006.01); C07D 267/08 (2006.01); C07D 487/10 (2006.01); C07D 265/28 (2006.01); A61K 31/665 (2006.01); A61K 31/553 (2006.01); A61K 31/505 (2006.01); A61K 31/527 (2006.01); A61K 31/535 (2006.01); A61K 31/537 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating those infected with HIV are encompassed.