The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7419834 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 02, 2008

Filed:

Dec. 12, 2002
Applicants:

Joan Mannick, Weston, MA (US);

Benjamin Gaston, Charlottesville, VA (US);

Barbara Leinweber, Eugene, OR (US);

Inventors:

Joan Mannick, Weston, MA (US);

Benjamin Gaston, Charlottesville, VA (US);

Barbara Leinweber, Eugene, OR (US);

Assignees:

University of Massachusetts, Boston, MA (US);

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 21/76 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention describes a novel, simplified method for detecting and monitoring whether the presence of nitrosylated proteins, such as S-nitrosoproteins, in a biological sample using fluorescence detection. The present invention further describes a method which can both quantify and identify the nature of nitrosylated proteins, which method is useful for monitoring both normal and disease states, in the development and screening of potential therapeutic drug species.


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