The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Oct. 21, 2003
Gregory L. Kirk, Winchester, MA (US);
Emanuele Ostuni, Watertown, MA (US);
Enoch Kim, Boston, MA (US);
Olivier Schueller, Arlington, MA (US);
Paul Sweetnam, Marblehead, MA (US);
Gregory L. Kirk, Winchester, MA (US);
Emanuele Ostuni, Watertown, MA (US);
Enoch Kim, Boston, MA (US);
Olivier Schueller, Arlington, MA (US);
Paul Sweetnam, Marblehead, MA (US);
Surface Logix, Inc., Brighton, MA (US);
Abstract
A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further provides a method of using the device to high-throughput screen a plurality of test agents. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed that mimic gradient situations present in vivo.