The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
May. 10, 2004
Timothy C. Dodge, Sunnyvale, CA (US);
Manoj Kumar, Fremont, CA (US);
M. Harunur Rashid, Sunnyvale, CA (US);
Fernando Valle, Burlingame, CA (US);
Timothy C. Dodge, Sunnyvale, CA (US);
Manoj Kumar, Fremont, CA (US);
M. Harunur Rashid, Sunnyvale, CA (US);
Fernando Valle, Burlingame, CA (US);
Danisco A/S, Genencor Division, Palo Alto, CA (US);
Abstract
The present invention relates to engineering metabolic pathways in bacterial host cells which results in enhanced carbon flow for the production of ascorbic acid (ASA) intermediates. In particular, the invention relates to increasing the production of ASA intermediates in bacterial cells by enhancing the availability of gluconate resulting from the inactivation of endogenous gluconate transporter genes.