The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Mar. 14, 2005
David S. F. Young, Toronto, CA;
Susan E. Hahn, Toronto, CA;
Fortunata Mcconkey, Shelburne, CA;
Michelle Kelleher, Wantage, GB;
Andrea Warner, Oxford, GB;
David S. F. Young, Toronto, CA;
Susan E. Hahn, Toronto, CA;
Fortunata McConkey, Shelburne, CA;
Michelle Kelleher, Wantage, GB;
Andrea Warner, Oxford, GB;
Arius Research Inc., Toronto, Ontario, CA;
Oxford Biomedica UK Ltd., Oxford, GB;
Abstract
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to such diagnosis and treatment which revolves around the ability of the 5LAC-23 monoclonal antibody (or antigenic binding fragments derived therefrom) to bind with the Laminin Receptor 1 Precursor Protein 37LRP; and most particularly to diagnosis and treatment of Hepatocellular Carcinoma by various means which rely upon direct binding of 5LAC-23 with the particular antigenic moiety specifically recognized thereby and generally overexpressed in Hepatocellular carcinoma cells. The invention additionally relates to the treatment of such cells with conjugated moieties effective to aid in differentiation, treatment and diagnostic imaging thereof.