The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2008
Filed:
Jul. 08, 2004
Jeffrey D. Chulay, Chapel Hill, NC (US);
Sergey Dryga, Chapel Hill, NC (US);
Elizabeth A. Reap, Durham, NC (US);
Robert A. Olmsted, Chapel Hill, NC (US);
John S. Morris, Cary, NC (US);
Jeffrey D. Chulay, Chapel Hill, NC (US);
Sergey Dryga, Chapel Hill, NC (US);
Elizabeth A. Reap, Durham, NC (US);
Robert A. Olmsted, Chapel Hill, NC (US);
John S. Morris, Cary, NC (US);
Alpha Vax, Inc., Research Triangle Park, NC (US);
Abstract
The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising alphavirus replicon RNAs, wherein a first replicon RNA comprises nucleic acid encoding cytomegalovirus pp65 and IE1 protein or immunogenic fragments thereof, and a second replicon RNA comprises nucleic acid encoding cytomegalovirus gB protein or an immunogenic fragment thereof, and wherein each of the two replicon RNAs is contained within a separate alphavirus replicon particle.