The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2008
Filed:
Oct. 05, 2004
Junichi Kobayashi, Nagano, JP;
Tetsuya Nakamura, Nagano, JP;
Hideyuki Muranaka, Nagano, JP;
Takehiro Ishikawa, Nagano, JP;
Tetsuro Tamai, Nagano, JP;
Satoshi Akahane, Nagano, JP;
Junichi Kobayashi, Nagano, JP;
Tetsuya Nakamura, Nagano, JP;
Hideyuki Muranaka, Nagano, JP;
Takehiro Ishikawa, Nagano, JP;
Tetsuro Tamai, Nagano, JP;
Satoshi Akahane, Nagano, JP;
Kissei Pharmaceutical Co., Ltd., Nagano, JP;
Abstract
The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein Ris hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R, Rand Ris independently hydrogen, halogen, lower alkyl or lower alkoxy; Ris hydrogen or lower alkyl; Ris hydrogen, halogen, lower alkyl, lower alkoxy, etc; Ris —COR, -A-COR, —O-A-COR, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, —OCH—, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.