The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2008

Filed:

Apr. 30, 2004
Applicants:

Jay S. Tung, Belmont, CA (US);

Albert W. Garofalo, South San Francisco, CA (US);

Michael A. Pleiss, Sunnyvale, CA (US);

Jing Wu, Redwood City, CA (US);

David W. G. Wone, Newark, CA (US);

Ashley C. Guinn, Santa Monica, CA (US);

Darren B. Dressen, San Mateo, CA (US);

R. Jeffrey Neitz, San Francisco, CA (US);

Jennifer Marugg, San Jose, CA (US);

Martin Neitzel, Pacifica, CA (US);

Inventors:

Jay S. Tung, Belmont, CA (US);

Albert W. Garofalo, South San Francisco, CA (US);

Michael A. Pleiss, Sunnyvale, CA (US);

Jing Wu, Redwood City, CA (US);

David W. G. Wone, Newark, CA (US);

Ashley C. Guinn, Santa Monica, CA (US);

Darren B. Dressen, San Mateo, CA (US);

R. Jeffrey Neitz, San Francisco, CA (US);

Jennifer Marugg, San Jose, CA (US);

Martin Neitzel, Pacifica, CA (US);

Assignee:

Elan Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 231/12 (2006.01); C07D 233/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds of formula I and II that are bradykinin Breceptor antagonists and are useful for treating diseases, or relieving adverse symptoms associated with disease conditions, in mammals mediated by bradykinin Breceptor. Certain of the compounds exhibit increased potency and are also expected to exhibit increased duration of action.


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