The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2008
Filed:
Feb. 20, 2004
Applicants:
Laura C. Blumberg, Waterford, CT (US);
Michael J. Munchhof, Salem, CT (US);
Andrei Shavnya, East Lyme, CT (US);
Inventors:
Laura C. Blumberg, Waterford, CT (US);
Michael J. Munchhof, Salem, CT (US);
Andrei Shavnya, East Lyme, CT (US);
Assignees:
Pfizer Inc., New York, NY (US);
Pfizer Products Inc., Groton, CT (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/538 (2006.01); A61K 31/519 (2006.01); A61K 31/517 (2006.01); A61K 31/5025 (2006.01); A61K 31/502 (2006.01); A61K 31/4439 (2006.01); A61K 31/437 (2006.01); A61K 31/4375 (2006.01); A61K 31/4704 (2006.01); C07D 265/36 (2006.01); C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 241/40 (2006.01); C07D 471/04 (2006.01); C07D 221/04 (2006.01); C07D 215/12 (2006.01); C07D 213/26 (2006.01);
U.S. Cl.
CPC ...
Abstract
Novel fused heteroaromatic compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of transforming growth factor ('TGF')-β signaling pathway. They are useful in the treatment of various TGF-related disease states including, for example, cancer and fibrotic diseases.