The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2008
Filed:
Aug. 29, 2006
Applicants:
Herbert Weissbach, Boynton Beach, FL (US);
Nathan Brot, West Orange, NJ (US);
Inventors:
Herbert Weissbach, Boynton Beach, FL (US);
Nathan Brot, West Orange, NJ (US);
Assignees:
Florida Atlantic University, Boca Raton, FL (US);
Hosptial for Special Surgery, New York, NY (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/44 (2006.01); C07D 209/04 (2006.01); C07D 305/14 (2006.01); C07D 307/02 (2006.01); C07D 305/12 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substates for enzymes of the methionine sulfoxide reductase (Msr) class. Some embodiments of the catalytic antioxidant compounds are derived from drugs with anti-inflammatory activity due to inhibition of cyclooxygenase enzymes.