The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2008
Filed:
Jun. 11, 2003
Dirk Kosemund, Erfurt, DE;
Gerd Mueller, Jena, DE;
Alexander Hillisch, Jena, DE;
Karl-heinrich Fritzemeier, Berlin, DE;
Peter Muhn, Berlin, DE;
Dirk Kosemund, Erfurt, DE;
Gerd Mueller, Jena, DE;
Alexander Hillisch, Jena, DE;
Karl-Heinrich Fritzemeier, Berlin, DE;
Peter Muhn, Berlin, DE;
Schering AG, Berlin, DE;
Abstract
This invention describes the new 9α-substituted estratrienes of general formula I in which R, R, R, R, Ras well as Rand Rhave the meanings that are indicated in the description and Rmeans a straight-chain or branched-chain, optionally partially or completely halogenated alkenyl radical with 2 to 6 carbon atoms, an ethinyl or prop-1-inyl radical, as pharmaceutical active ingredients that exhibit in vitro a higher affinity to estrogen receptor preparations from rat prostates than to estrogen receptor preparations from rat uteri and in vivo preferably a preferential action on the ovary in comparison to the uterus, their production, their therapeutic use and pharmaceutical dispensing forms that contain the new compounds. The invention also describes the use of these compounds for treating estrogen-deficiency-induced diseases and conditions.