The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2008
Filed:
Oct. 19, 2004
Krishna G. Peri, St-Laurent, CA;
Serge Moffett, St-Laurent, CA;
Daniel Abran, Vaudreuil, CA;
Annie Bergeron, Repentigny, CA;
Krishna G. Peri, St-Laurent, CA;
Serge Moffett, St-Laurent, CA;
Daniel Abran, Vaudreuil, CA;
Annie Bergeron, Repentigny, CA;
Theratechnologies, Inc., Saint-Laurent, Quebec, CA;
Abstract
Antagonistic peptides of prostaglandin E2 receptor subtype EP4 and their use in the treatment or prevention of medical conditions associated with oligouric nephropathy, bone resorption, abnormal intestinal crypt cell proliferation or patency of the ductus arteriosus and the like are provided herein. The antagonistic peptides of the present invention can include the following formula:X-A-RYwherein 'X' is a hydrogen atom or an amine protecting group producing a carbamate or an amide when reacting with the amine; 'A' is L-(4,4')-biphenylalanine or D-(4,4′)-biphenylalanine; “R” is an amino acid selected from the group consisting of threonine, serine, tyrosine, glutamic acid, alanine, leucine and glycine; “Y” is lysine; “n” is an integer ranging from 5 to 7; and “m” is an integer ranging from 0 to 2.