The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2008
Filed:
Aug. 21, 2007
Applicants:
Sheng-yun Liu, Taipei Hsien, TW;
Mao-tien Kuo, Taipei Hsien, TW;
Wu-che Wen, Taipei Hsien, TW;
Inventors:
Assignee:
Golden Biotechnology Corporation, Taipei Hsien, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/12 (2006.01); C07C 49/543 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to a compound ofused to inhibit HBV, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone which is isolated fromand its use in inhibiting HBV effectively. The cyclohexenone compound according to the present invention showed cytotoxicity on HBV-secreting human hepatoma cell line HepG2 2.2.15, decreased synthesis of HBV particles, further inhibited synthesis of HbsAg and HbeAg effectively to achieve the goal of HBV inhibition.