The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2008
Filed:
Nov. 19, 2001
Toshiki Murata, Ikoma, JP;
Sachiko Sasaki, Ikoma, JP;
Takashi Yoshino, Nara, JP;
Yuka Ikegami, Kyoto-fu, JP;
Tsutomu Masuda, Nara, JP;
Mitsuyuki Shimada, Nara, JP;
Takuya Shintani, Kyoto-fu, JP;
Makoto Shimazaki, Kyoto-fu, JP;
Timothy B. Lowinger, Wuppertal, DE;
Karl B. Ziegelbauer, Haan, DE;
Kinji Fuchikami, Kyoto-fu, JP;
Masaomi Umeda, Nara, JP;
Hiroshi Komura, Nara, JP;
Nagahiro Yoshida, Kyoto-fu, JP;
Toshiki Murata, Ikoma, JP;
Sachiko Sasaki, Ikoma, JP;
Takashi Yoshino, Nara, JP;
Yuka Ikegami, Kyoto-fu, JP;
Tsutomu Masuda, Nara, JP;
Mitsuyuki Shimada, Nara, JP;
Takuya Shintani, Kyoto-fu, JP;
Makoto Shimazaki, Kyoto-fu, JP;
Timothy B. Lowinger, Wuppertal, DE;
Karl B. Ziegelbauer, Haan, DE;
Kinji Fuchikami, Kyoto-fu, JP;
Masaomi Umeda, Nara, JP;
Hiroshi Komura, Nara, JP;
Nagahiro Yoshida, Kyoto-fu, JP;
Bayer Aktiengesellschaft, Leverkusen, DE;
Abstract
4-aryl pyrimidine compounds of general formula and salts thereof: wherein X is CH or N; R1 is hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, etc.; R2 is hydrogen or hydroxy; R3 is hydrogen, C1-6 alkyl, etc.; R4 is hydrogen, hydroxy, halogen, amino, etc.; R5 is hydroxy, amino, carboxy, etc.; R6 is hydrogen, carbamoyl, cyano, carboxy, C1-6 alkoxycarbonyl, etc. and R7 is amino or C1-6 alkanoylamino. The compounds (I) or the salts thereof have an excellent anti-inflammatory activity and the like.