The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2008

Filed:

Apr. 14, 2006
Applicants:

Victor C. W. Tsang, Decatur, GA (US);

Jeffrey L. Call, Logan, UT (US);

Yeuk-mui Lee, Lilburn, GA (US);

Kathy Hancock, Atlanta, GA (US);

Inventors:

Victor C. W. Tsang, Decatur, GA (US);

Jeffrey L. Call, Logan, UT (US);

Yeuk-mui Lee, Lilburn, GA (US);

Kathy Hancock, Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

A reagent and method for the specific and highly sensitive detection ofin which the reagent is an antibody for a solublesporozoite antigen and the method is an immunoassay in which the antibody is used to detect or quantifysporozoite antigen in a sample. The sample is treated to cause excystation ofoocytes, thereby releasing asporozoite antigen, and combined with antibodies specific for the sporozoite antigen under conditions to form an antibody-antigen complex. Detection of the complex indicates the presence ofin the sample. The assay allows recognition and detection ofin turbid samples, and due to a lack of crossreactivity with otherspecies, is specific forcontamination or infection. The assay is highly sensitive, allowing for the detection of less than 100 oocysts per milliliter of sample.


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