The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2008

Filed:

Jan. 10, 2003
Applicants:

Martin Gilbert Pomper, Baltimore, MD (US);

Jiazhong Zhang, Washington, DC (US);

Alan P. Kozikowski, Princeton, NJ (US);

John L. Musachio, Lutherville, MD (US);

Inventors:

Martin Gilbert Pomper, Baltimore, MD (US);

Jiazhong Zhang, Washington, DC (US);

Alan P. Kozikowski, Princeton, NJ (US);

John L. Musachio, Lutherville, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 241/00 (2006.01); C07C 57/30 (2006.01); C07C 229/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express NAALADase and/or PSMA. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express NAALADase and/or PSMA to which the compounds of the invention have an affinity.


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