The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2008

Filed:

Jan. 20, 2004
Applicants:

Jonathan S. Lindsey, Raleigh, NC (US);

Masahiko Taniguchi, Raleigh, NC (US);

Sreedharan Prathapan, Kerala, IN;

Han-je Kim, Raleigh, NC (US);

Man Nyoung Kim, Daejeon, KR;

Inventors:

Jonathan S. Lindsey, Raleigh, NC (US);

Masahiko Taniguchi, Raleigh, NC (US);

Sreedharan Prathapan, Kerala, IN;

Han-Je Kim, Raleigh, NC (US);

Man Nyoung Kim, Daejeon, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07B 47/00 (2006.01); C07D 345/00 (2006.01); C07D 517/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydronchlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.


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