The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2008
Filed:
Nov. 23, 2004
Katherine S. Bowdish, Del Mar, CA (US);
John Mcwhirter, San Diego, CA (US);
Anke Kretz-rommel, San Diego, CA (US);
Toshiaki Maruyama, La Jolla, CA (US);
Katherine S. Bowdish, Del Mar, CA (US);
John McWhirter, San Diego, CA (US);
Anke Kretz-Rommel, San Diego, CA (US);
Toshiaki Maruyama, La Jolla, CA (US);
Alexion Pharmaceuticals, Inc., Cheshire, CT (US);
Abstract
Cancer treatments use a therapy that: 1) interferes with the interaction between CD200 and its receptor to block immune suppression thereby promoting eradication of the cancer cells; and 2) directly kills the cancer cells either by complement-mediated or antibody-dependent cellular cytotoxicity or by targeting cells using a fusion molecule that includes a CD200-targeting portion. The therapy includes the administration of novel antibodies, functional fragments thereof or fusion molecules containing portions thereof.