The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2008
Filed:
Jan. 13, 2005
Ruben Carbonell, Raleigh, NC (US);
Haiou Yang, Raleigh, NC (US);
Patrick Gurgel, Cary, NC (US);
North Carolina State University, Raleigh, NC (US);
Abstract
An immunoglobulin binding peptide having the general formula, from amino terminus to carboxy terminus, of Z-R—R—R—R—R—R—X, is described, wherein: Ris H or Y; Ris a hydrophobic, preferentially aromatic, amino acid (for example W, F, Y, V); Ris a positively charged or aromatic amino acid (for example R, H, F, W); Ris a hydrophobic or positively charged amino acid (for example G, Y, R, K, L); Ris a positively charged or aromatic amino acid (for example W, F, R, H, Y); Ra random amino acid but preferably hydrophobic or negatively charged (for example V, W, L, D, H); X is present or absent and when present is a linking group; and Z is present or absent and when present is a capping group bonded to the N terminus of R; and wherein the amino acids of said peptide are in D form, L form, or a combination thereof. Methods of using such peptides for the purification of Immunoglobulins are also described.