The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2008
Filed:
Oct. 07, 2004
Dale S. Dhanoa, Wakefield, MA (US);
Oren Becker, Mevaseret Zion, IL;
Silvia Noiman, Herzliya, IL;
Laurence Wu, Woburn, MA (US);
Mercedes Lobera, Concord, MA (US);
Pradyumna Mohanty, Woburn, MA (US);
Yael Marantz, Kadima, IL;
Boaz Inbal, Kfar Shmuel, IL;
Sharon Shacham, Alfey Menashe, IL;
Dongli Chen, Chestnut Hill, MA (US);
Dale S. Dhanoa, Wakefield, MA (US);
Oren Becker, Mevaseret Zion, IL;
Silvia Noiman, Herzliya, IL;
Laurence Wu, Woburn, MA (US);
Mercedes Lobera, Concord, MA (US);
Pradyumna Mohanty, Woburn, MA (US);
Yael Marantz, Kadima, IL;
Boaz Inbal, Kfar Shmuel, IL;
Sharon Shacham, Alfey Menashe, IL;
Dongli Chen, Chestnut Hill, MA (US);
Epix Delaware, Inc., Lexington, MA (US);
Abstract
The invention relates to 5-HTreceptor agonists and partial agonists. Thienopyridinone compounds and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HTreceptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, Parkinson's disease, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, and nonulcer dyspepsia. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.