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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7407961 B1

PDFFull Text
Expired
Date of Patent:
Aug. 05, 2008

Filed:

Oct. 26, 2004

Pyrazine derivatives and pharmaceutical use thereof

Applicants:

Satoshi Yonishi, Osaka, JP;

Satoshi Aoki, Osaka, JP;

Yuji Matsushima, Osaka, JP;

Atsushi Akahane, Osaka, JP;

Inventors:

Satoshi Yonishi, Osaka, JP;

Satoshi Aoki, Osaka, JP;

Yuji Matsushima, Osaka, JP;

Atsushi Akahane, Osaka, JP;

Assignee:

Astellas Pharma Inc., Tokyo, JP;

Attorney:

Oblon, Spivak, McClelland, Maier & Neustadt, P.C.

Primary Examiner:

Zachary C Tucker

Int. Cl.
CPC ...
A61K 31/4965 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A pyrazine derivative of the following formula (I): or a salt thereof. The pyrazine compound (I) and a salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.

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Yonishi, Satoshi. (2008). Pyrazine derivatives and pharmaceutical use thereof (U.S. Patent No. 7407961). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7407961

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