The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2008
Filed:
Jul. 06, 2005
Gangadhar Nagula, Nashha, NH (US);
Jan Urban, San Diego, CA (US);
Hwa-ok Kim, Lexington, MA (US);
Christopher Lum, Kirkland, WA (US);
Hiroshi Nakanishi, San Diego, CA (US);
Gangadhar Nagula, Nashha, NH (US);
Jan Urban, San Diego, CA (US);
Hwa-Ok Kim, Lexington, MA (US);
Christopher Lum, Kirkland, WA (US);
Hiroshi Nakanishi, San Diego, CA (US);
Myriad Genetics, Inc., Salt Lake City, UT (US);
Abstract
Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins having the following structure are disclosed: wherein A, R, R, Rand Rare as defined herein. Such compounds have utility over a wide range of fields, including use as diagnostic and therapeutic agents. In particular, compounds of this invention are useful in pharmaceutical compositions as anti-inflammatory agents as well as inhibitors of central nervous disorders. Libraries containing the compounds of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.