The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2008
Filed:
Nov. 27, 2000
Hajime Fujisawa, Kasugai, JP;
Toru Kimura, Kusatsu, JP;
Kaoru Kikuchi, Takarazuka, JP;
Yasunori Murakami, Kobe, JP;
Hajime Fujisawa, Kasugai, JP;
Toru Kimura, Kusatsu, JP;
Kaoru Kikuchi, Takarazuka, JP;
Yasunori Murakami, Kobe, JP;
Japan Science and Technology Agency, Kawaguchi-shi, Saitama, JP;
Dainippon Sumitomo Pharma Co., Ltd., Chuo-ku, Osaka-shi, JP;
Abstract
The present invention provides screening methods for agonists or antagonists of Sema6C using Plexin-A1, and tools for the screening and the like. It evaluates a case of making a recombinant protein having an extracellular domain of Semaphorin 6C contact a protein having an extracellular domain of Plexin-A1 by comparing it with a case of contacting a recombinant protein and a target substance having an extracellular domain of Semaphorin 6C, or the target substance with a protein having an extracellular domain of Plexin-A1. The evaluation will be carried out by the connectivity of a protein having an extracellular domain of Semaphorin 6C, a growth cone collapse activity of Plexin-A1 expressing cell, or a contractile activity of Plexin-A1 expressing cell.