The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2008

Filed:

Apr. 21, 2004
Applicants:

John D. Kriesel, Holladay, UT (US);

Brandt B. Jones, Bountiful, UT (US);

Charles B. Grissom, Salt Lake City, UT (US);

Geoff Herpin, Salt Lake City, UT (US);

Peter M. Glazer, Guilford, CT (US);

Inventors:

John D. Kriesel, Holladay, UT (US);

Brandt B. Jones, Bountiful, UT (US);

Charles B. Grissom, Salt Lake City, UT (US);

Geoff Herpin, Salt Lake City, UT (US);

Peter M. Glazer, Guilford, CT (US);

Assignees:

University of Utah Research Foundation, Salt Lake City, UT (US);

Yale University, New Haven, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); A61K 39/245 (2006.01);
U.S. Cl.
CPC ...
Abstract

The methods disclosed herein are of use for the treatment of a wide variety of diseases. In particular, the methods provide for the targeting of a transcription altering agent to a specific target site of a viral genome in order to inactivate the virus. In addition, the methods provide for a triplex-forming oligonucleotide capable of interacting with a target site in a viral genome in order to alter transcription. The methods of the present invention may be used against viral pathogens or agents of bioterrorism.


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