The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2008
Filed:
Sep. 20, 2002
Marcel Loetscher, Maennedorf, CH;
Bernhard Moser, Utzenstorf, CH;
Shixin Qin, Lexington, MA (US);
Charles R. Mackay, Vancluse, AU;
Marcel Loetscher, Maennedorf, CH;
Bernhard Moser, Utzenstorf, CH;
Shixin Qin, Lexington, MA (US);
Charles R. Mackay, Vancluse, AU;
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Theodor-Kocher Institute, Bern, CH;
Abstract
The present invention relates to proteins or polypeptides, referred to herein as isolated and/or recombinant mammalian (e.g., human) IP-10/Mig receptor proteins designated CXC Chemokine Receptor 3 (CXCR3) and variants thereof, including those characterized by selective binding of one or more chemokines (e.g., IP-10 and/or Mig), and/or the ability to induce a cellular response (e.g., chemotaxis, exocytosis). Antibodies reactive with CXCR3 receptors can be produced using the proteins or variants thereof or host cells comprising same as immunogen.