The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2008

Filed:

Nov. 24, 2003
Applicants:

Douglas Wade Beight, Frankfort, IN (US);

Timothy Paul Burkholder, Carmel, IN (US);

Todd Vincent Decollo, Noblesville, IN (US);

Alexander Glenn Godfrey, Mooresville, IN (US);

Charles Raymond Heap, West Sand Lake, NY (US);

Chi-hsin Richard King, Slingerlands, NY (US);

Hong-yu LI, Zionsville, IN (US);

William Thomas Mcmillen, McCordsville, IN (US);

Jason Scott Sawyer, Indianapolis, IN (US);

Yan Wang, Carmel, IN (US);

Clive Gideon Diefenbacher, Greenwood, IN (US);

Thomas Albert Engler, Indianapolis, IN (US);

Sushant Malhotra, Indianapolis, IN (US);

Sreenivasa Reedy Mundla, Westfield, IN (US);

Inventors:

Douglas Wade Beight, Frankfort, IN (US);

Timothy Paul Burkholder, Carmel, IN (US);

Todd Vincent Decollo, Noblesville, IN (US);

Alexander Glenn Godfrey, Mooresville, IN (US);

Charles Raymond Heap, West Sand Lake, NY (US);

Chi-Hsin Richard King, Slingerlands, NY (US);

Hong-Yu Li, Zionsville, IN (US);

William Thomas McMillen, McCordsville, IN (US);

Jason Scott Sawyer, Indianapolis, IN (US);

Yan Wang, Carmel, IN (US);

Clive Gideon Diefenbacher, Greenwood, IN (US);

Thomas Albert Engler, Indianapolis, IN (US);

Sushant Malhotra, Indianapolis, IN (US);

Sreenivasa Reedy Mundla, Westfield, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 241/36 (2006.01); C07D 217/00 (2006.01); C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The current invention relates to compounds of the formula: (Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.


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